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Page Title: DISEASES OF THE CIRCULATORY SYSTEM
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DISEASES OF THE GENITOURINARY  (GU)  TRACT
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antibiotics,   analgesics,   and   sometimes   infil- tration  of  the  spermatic  cord  with  procaine hydrochloride. Renal Calculi Renal  calculi  are  concentrations  of  mineral salts   and   crystals   commonly   called   stones. Many  theories  and  factors  have  been  advanced as  causes  of  calculi.  Among  these  are  excessive intake  of  milk  (calcium),  previous  infection, sulfonamide  therapy,  metabolic  disease,  dehydra- tion,  or  exposure  to  intensely  hot  climates. Also  chronic  pyelonephritis  often  predisposes  to calculi. SYMPTOMS—Excruciating intermittent pain that  originates  in  the  flank  or  kidney  area  and radiates  across  the  abdomen  and  along  the  course of  the  ureters  is  common.  Frequently  the  pain radiates  into  the  genitalia  and  along  the  inner aspects   of   the   thighs.   Chills,   fever,   and frequency and urgency of urination, despite pain, is   common. Hematuria  is  usally  present. Vomiting,   diaphoresis,   and   shock   may   occur. Screening   the   urine   may   produce   crystalline substances.  Anuria  indicates  renal  failure  and leads to uremia. TREATMENT—Many  solitary  calculi,  unac- companied  by  obstruction  or  infection,  require no specific therapy. Force fluids and restrict the intake   of   calcium.   Antibiotics,   Demerol®,  or morphine  are  indicated.  Do  not  give  anti- spasmodic.  Bed  rest  and  supportive  treatment  are indicated.  Stones  that  are  obstructive  must  be surgically    removed.    Hospitalize  as  soon  as possible. Uremia Uremia is a toxic condition produced by renal failure  and  retention  of  waste  products  in  the circulatory  system. SYMPTOMS—At  first,  weakness,  anorexia, nausea,  and  vomiting,  headache,  vertigo,  and dimness  of  vision  may  occur.  Later  there  is extreme  restlessness,  insomnia,  twitching,  urinous odor  to  the  breath,  perspiration,  waxy  pallor, edema,  coma,  and  convulsions. TREATMENT—Fluid  replacement  to  equal the amount of urinary output plus the amount of insensible  fluid  loss  should  be  effected.  Specific therapy is aimed at treating the underlying cause, such  as  congestive  heart  failure,  infection,  or obstruction.  Hospitalize  immediately. Testicular Torsion This  condition  is  the  result  of  twisting  the testes. It may occur spontaneously as the result of emotional stress or as the result of strenuous activity  or  exercise. SYMPTOMS—There   is   a   sudden   onset   of intense   pain,   and   the   pain   is   aggravated   by elevating  the  scrotum.  This  is  the  essential diagnostic  difference  between  testicular  torsion and epididymitis. The twisted testicle is normally higher and closer to the external ring. The patient demonstrates   nausea,   vomiting,   pallor,   and syncope. The color of the scrotum on the affected side is pink and swelling is rapid. TREATMENT—This   is   an   emergency!   Im- mediate surgical correction is essential to avoid gangrene  due  to  vascular  occlusion.  Administer meperidine  or  morphine  for  intense  pain. Genitourinary Trauma This   condition   is   normally   caused   by penetrating   and   perforating   wounds,   blunt crushing  injuries,  surgery,  or  irradiation.  The kidney  is  most  often  injured  by  blunt  external force  to  the  flank  or  abdomen.  Rupture  of  the bladder  occurs  when  the  bladder  is  over  distended and  external  force  is  applied.  Injuries  to  the urethra are caused by pelvic fractures. Crushing or avulsion  is  the  main  cause  of  injury  to  the genitalia. TREATMENT—In  all  cases  of  serious  GU trauma, the patient should be hospitalized as soon as possible, since in most cases, surgical correc- tion  will  normally  be  required.  In  all  injuries, gangrene and tetanus are serious possibilities. In case  of  avulsions,  retain  the  avulsed  tissue  and refrigerate it immediately. Treat for shock, give analgesics,  and  force  fluids. DISEASES OF THE CIRCULATORY  SYSTEM Rheumatic  Fever This  acute,  infectious,  noncontagious  systemic disease is most commonly found in children and 2-14

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