USUAL DOSE. As with chlorpromazine,
dosages are highly individualized and may range
from 0.5 mg to 8 mg or higher on a daily basis.
Lithium (Eskalith, Lithane)
ACTION AND USE. Lithium is used in the
treatment of manic episodes of manic-depressive
illness. It is the drug of choice to prevent or
diminish the intensity of manic episodes.
USUAL DOSE. Dosage must be individ-
ualized according to serum levels and clinical
response. Give 600 mg three times daily or 900
mg twice daily for the slow release form.
Amitriptyline Hydrochloride (Elavil)
ACTION AND USE. Amitriptyline is an
antidepressive mood elevator with mild tranquiliz-
ing effects. It is indicated for the long-term treat-
ment of depressive disorders.
USUAL DOSE. Initially, 75 mg daily in
three divided doses but may be increased to 150
mg daily dependant on clinical response.
Chlordiazepoxide Hydrochloride (Librium)
ACTION AND USE. Chlordiazepoxide
hydrochloride is an antianxiety agent indicated for
the treatment of anxiety disorders. It is not in-
dicated for anxiety or tension associated with the
stress of everyday activities. It is also indicated
in the abatement of acute withdrawal symptoms
USUAL DOSE. Optimum dose is dependant
upon the patients condition and clinical response.
It may range from 5 mg 3 or 4 times daily to 25
mg 3 or 4 times daily.
Hydroxizine Hydrochloride (Vistaril)
ACTION AND USE. Hydroxizine Hydro-
chloride is a rapid acting anti-anxiety and anti-
emetic with antispasmodic and muscle relaxant
effects. It is most often used in pre- and post-
operative sedation and in conjunction with
meperidine hydrochloride to potentate its effects
and reduce nausea. It is for intramuscular or oral
use only, not for intravenous use.
USUAL DOSE. 50 mg is the normal dose
with ranges from 25 to 100 mg.
ACTION AND USE. Diazepam is useful in
treating mild to moderate depression with anxiety
and tension. Because of its muscle relaxant
properties, it is also used to treat spastic muscle
conditions and convulsive seizure episodes; it is
the drug of choice in status epileptics. Diazepam
is probably one of the most abused of the prescrip-
tion drugs and has both psychological and
physical dependence properties. Withdrawal
symptoms may manifest with sudden cessation
after long-term use.
USUAL DOSE. Dosages may range from 2
to 40 mg daily in 2 to 4 equally divided doses.
ACTION AND USE. Flurazepam is a hyp-
notic indicated for the treatment of insomnia.
USUAL DOSE. 15 to 30 mg at bedtime.
SKELETAL MUSCLE RELAXANTS
These agents may be used to produce muscular
relaxation during surgical anesthesia. More often
these drugs are used in connection with the treat-
ment of muscle spasm due to various conditions.
All of these drugs may cause drowsiness and im-
pair performance of tasks that require alertness.
ACTION AND USE. Methocarbamol is
used as an adjunct to rest, physical therapy, and
other measures for the relief of discomfort
associated with acute, painful musculoskeletal
USUAL DOSE. 1 g four times daily, or 1.5
g two or three times daily.
Cyclobenzaprine Hydrochloride (Flexeril)
ACTION AND USE. Cyclobcnzaprine
hydrochloride is indicated for short term treat-
ment of skeletal muscle spasms of local origin.
USUAL DOSE. 10 mg three times daily for
up to three weeks.